Introducing Cellarator® Advantage RECOVERY+

Performance horses have their limits tested constantly. That’s why it’s important that we invest in their health. Cellarator® Advantage RECOVERY+ is a new, one-of-a-kind supplement designed specifically to help the performance horse recover from exercise-induced muscle damage. Reactive oxygen species (ROS) produced in the muscles during exercise can overwhelm the body’s natural ability to recover. This oxidative stress damages muscle protein, lipid, and DNA and causes the release of pro-inflammatory cytokines. The end result is muscle pain and reduced performance. The exclusive Cellarator® Advantage RECOVERY+ formula contains unique ingredients proven to combat these issues, improve energy utilization, and support overall muscle recovery and repair.

Ingredient Research

Cellarator® Advantage RECOVERY+ contains a unique blend of ingredients, each backed with clinical research to support their efficacy in muscle recovery. Astaxanthin, a marine-derived carotenoid, has been shown to decrease the clinical signs of muscle damage and exertional rhabdomyolysis in exercising Thoroughbreds1. This is likely attributed to its strong ROS scavenging and quenching activity which is 6,000 times greater than vitamin C and over 500 times greater than vitamin E2. Astaxanthin has been reported to decrease lipid peroxidation3 and improve energy production through the decrease of oxidative damage of carnitine palmitoyltransferase 1 (CPT1) and reduction in blood lactate4. In addition to branched chain amino acids, Recovery Plus also contains dietary nucleotides. These precursors to RNA and DNA have been shown to be a potent immunomodulator whereby helping reverse immune suppression associated with stress5,6. Although the exact mechanisms are multifactorial in nature, research has demonstrated exogenous nucleotides can enhance lymphocyte maturation, activation, and proliferation7. Exogenous nucleotides have also been reported to reduce protein catabolism and blood lactate after forced exercise8.

Feeding Directions & Intended Use

Feed 1 scoop (1 ounce) per head daily, either top-dressed or mixed with other feeds. Cellarator® Advantage RECOVERY+ is not a complete feed and should be fed with additional feed to meet the animal’s nutrient requirements, along with clean, potable water. Provides support for horses with chronic muscle soreness by helping alleviate the negative effects of exercise-induced muscle damage including exertional rhabdomyolysis and impeding oxidative damage and promoting amino acid accretion.

A Global Leader in Equine Nutrition

ADM provides high-quality, sustainable animal nutrition solutions that meet your changing needs. With experienced equine specialists and nutritionists, a continuously growing product portfolio and access to global innovations, we work with you to advance nutritional performance and develop solutions to drive success today and tomorrow.

1. Sato F., T. Omuraa, M. Ishimarua, Y. Endoa, H. Murasea, E. Yamashitab. 2015. Effects of Daily. Astaxanthin and L-Carnitine Supplementation for Exercise-Induced Muscle Damage in Training. Thoroughbred Horses J. of Equine Vet. Sci. 35(10):836–842

2. Nishida,Y., E. Yamashita, W. Miki. 2007. Quenching activities of common hydrophilic and lipophilic antioxidants against singlet oxygen using chemiluminescence detection system. Carotenoid Science, 11:16-20.

3. Goto, S., K. Kogurea, K. Abea, Y. Kimataa, K. Kitahamaa, E. Yamashitab, H. Teradaa. 2001. Efficient radical trapping at the surface and inside the phospholipid membrane is responsible for highly potent antiperoxidative activity of the carotenoid astaxanthin. Biochim. Biophys. Acta, 1512: 251-258.

4. Aoi, W., Y. Naito, Y. Takanami, T. Ishii, Y. Kawai, S. Akagiri, Y. Kato, T. Osawa, T. Yoshikawa. 2008. Astaxanthin improves muscle lipid metabolism in exercise via inhibitory effect of oxidative CPT I modification. Biochem. Biophys. Res. Commun., 366:892-897

5. Pickering L.K., D.M. Granoff, J.R. Erickson, M.L Masor, C.T. Cordle, J.P Schaller, T.R. Winship, C.L. Paule, M.D. Hilty. 1998. Modulation of the immune system by human milk and infant formula containing nucleotides. Pediatrics. 101: 242-249.

6. Riera J., V. Pons, D. Martinez-Puig, C. Chetrit, J.A Tur, A. Pons, F. Drobnic. 2013. Dietary nucleotide improves markers of immune response to strenuous exercise under a cold environment. J. Int. Soc. Sports Nutr. 10(20).

7. Gil A., O. Martínez-Augustín, J. Navarro. 1973. Role of dietary nucleotides in the modulation of the immune response. Neonatal hematology and immunology III. Edited by: J.A. Bellanti, et al., Elsevier Science, Amsterdam, 139-144.

8. Xu, M., R. Liang, Y. Li, J. Wang. 2017. Anti-fatigue effects of dietary nucleotides in mice. Food Nutr. Res. 61, 1334485.

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